Routine analysis by the ARUP drug detection panel includes qualitative detection by mass spectrometric methods for all compounds (eg, opioids, stimulants, sedative-hypnotics). Meconium specimen is limited or unavailableĬord tissue specimen is limited or unavailable Preferred for the detection of gabapentin, fentanyl, meperidine, propoxyphene, tramadol, tapentadol, phentermine, and/or zolpidem Most sensitive and definitive testing for heroin use Most sensitive and definitive testing for cannabis use Traditional testing approach (screen with reflex to confirmation testing) preferred Tracking of specimen collection and handling process requiredįastest available time to result when positive results are expected Preferred process for collection is at birth, for all infants test immediately for high-risk births, store for low-risk birthsĬollection based on need (eg, history of drug exposure, maternal urine screen results, NAS symptoms/diagnosis) Umbilical Cord Tissue vs Meconium Testing Factors to Consider There are several factors to consider when deciding whether to use umbilical cord tissue or meconium for drug testing. Contact ARUP Client Services for more information. ARUP offers a specimen tracking form for documentation of the collection, handling, and shipping of specimens. NOTE: Umbilical cord tissue and meconium drug tests are performed to support clinical and social management decisions and do not usually require chain of custody. Grows with fetus throughout pregnancy (nonlinear process)ĭrugs appear to deposit consistently across length of cordĬoncentrations of drug analytes are lower in cord than in meconium, but can be detected with appropriate methodologyĭrug detection in cord tissue depends on many factors (eg, quality and completeness of collection, drug use patterns) Newborn Drug Testing Specimen Types MeconiumĪccumulates over remainder of pregnancy (nonlinear process)Ĭollection requires coordinated efforts and may not be availableĭrug detection in meconium depends on many factors (eg, quality and completeness of collection, drug use patterns) Urine tests generally detect only recent maternal drug use in the days before delivery. Available Specimen TypesĪRUP offers newborn drug testing for two specimen types: umbilical cord tissue and meconium. Urine as a specimen type for neonatal drug testing has limited success the first void is often missed because it may occur during or immediately after delivery. Newborn drug testing is recommended in infants born to mothers with high-risk behaviors (eg, history of drug use/abuse, prostitution, nicotine use), minimal or no prenatal care, or unexplained obstetric events (eg, placental abruption, premature labor).Īdditionally, infants with unexplained neurologic complications, unexpected intrauterine growth retardation, or drug withdrawal symptoms (eg, NAS) should be tested for drug exposure.
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January 2023
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